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Senior Research Investigator
San Antonio, TX 

The USAISR is dedicated to both laboratory and clinical trauma research. Its mission is to provide requirements-driven combat casualty care medical solutions and products for injured soldiers from self-aid through definitive care across the full spectrum of military operations; provide state-of-the-art trauma, burn, and critical care to Department of Defense (DoD) beneficiaries around the world; and provide Burn Special Medical Augmentation Response Teams (BSMART). Within the USAISR, the Joint Trauma System (JTS) was established in order to improve combat casualty care across the continuum of care and to maintain the Department of Defense Trauma Registry (DoDTR) and the Military Orthopaedic Trauma Registry (MOTR).  


This positions work with the mission of the nation’s premier joint research organization planning and executing registry-based and translational research providing innovative solutions for burn, trauma, and combat casualty care from the point of injury through rehabilitation.    There is one position in each of the following task areas:

 Coagulation and Blood Research. This competency requires planning, conducting and coordinating the research of diagnostics and therapeutics to treat the Coagulopathy of Trauma, support resuscitation of critically injured patients, and mitigate multi-organ failure with safe and effective blood products and cellular therapies far forward of fixed medical facilities. 

Damage Control Resuscitation Research.  This competency requires conducting, coordinating, and support research identifying solutions to deficits associated with the control of bleeding and the stabilization of injured soldiers with the emphasis of treatments far forward of fixed Medical facilities. Identification of potential solutions include evaluating advanced endovascular mechanical devices for hemorrhage control and defining strategies for mechanical hemorrhage interventions.

We are seeking a Senior Research Investigator to perform laboratory research to satisfy the mission support requirements at the U.S. Army Institute of Surgical Research (USAISR) 


  • Conduct animal research to satisfy mission support requirements such as:
    • Maintain current with and comply with animal use directives applicable to USAISR. 
    • Perform animal surgery to include both routine catheterizations and complex cardiovascular and neurological surgery.
    • Perform all aspects of critical care management of critically ill, mechanically ventilated animals. 
    • Operate a variety of clinical and experimental monitors and life support systems, to include mechanical ventilators, data acquisition systems, pulmonary mechanics monitors, and intra-as well as extracorporeal oxygenation circuits. 
    • Perform and oversee surgical trauma and bleeding protocols, and collection of blood and tissue samples.
    • Perform 3- dimensional image reconstruction and quantitative analysis of X-rays or CT scans.
    • Analyze physiologic waveforms data by time, spectral, and fractal techniques using commercial software.
    • Take a lead role with animal research team and serve as an investigator on animal protocols.
  • Apply for funding, review scientific documentation and literature, and establish and maintain collaborations as force multipliers to expand capabilities such as:
    • Draft, revise, and submit proposals for intramural, DHP, and extramural funding.
    • Perform scientific peer review for local protocols. 
    • Work in collaboration with industry and academic partners under CRADAs. 
    • Provide consultation on relevant complex projects to DoD members as well as external Collaborators. 


  • PhD degree in a Biological Science of MD
  • 2 years’ experience in Biological Science Research
  • Must have large animal surgery experience 
  • Desire to have some military research background
  • Must have prior experience in working with in Animal Research
  • Experience with all aspects of critical care management of critically ill, mechanically ventilated animals. 
  • Expertise in working with surgical trauma and bleeding protocols
  • Knowledge of working commercial software to analyze physiologic waveforms date by time, spectral and fractal techniques.
  • Have a working knowledge of the DOD  community
  • Possesses good written and oral communication skills, and will be expected to write reports and publications, and present their findings in meetings.
  • Must maintain current knowledge of developments in the field of trauma, critical care and hemorrhagic shock research, and transfusion medicine. 
  • Must be proficient at use software: Excel, Word, PowerPoint, JMP, Sigma Plot/Stat, and Graph Pad Prism to organize

Work Environment
The duties of this position are primarily performed in a climate controlled 100% secured office environment. It site right next to large military hospital. Within this building we do conduct animal reach. All successful candidate will have to meet the USAISR Health requirements. New hire will comply with safety procedures and infection control/occupational health procedures pertaining to the entire ISR facility, but in particular to the laboratory, vivarium and animal surgery area. This may include documentation of the following: TB Test; Hepatitis B vaccine, titer, or wavier, Toxoplasmosis titer (females); Rabies (pre-bite) vaccine, titer, or wavier, Brucellosis titer; Q-Fever titer, Tetanus booster within the last 5; HIV titer, as required. Other special exam such as pulmonary function, respirator fit, audiogram and/or laser vision testing may also be required.  

Applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for access to classified information.

Apply online at

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